Temozolomide Resistance in Glioblastoma Cell Lines: Implication of MGMT, MMR, P-Glycoprotein and CD1...
Temozolomide Resistance in Glioblastoma Cell Lines: Implication of MGMT, MMR, P-Glycoprotein and CD133 Expression
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United States: Public Library of Science
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English
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United States: Public Library of Science
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The use of temozolomide (TMZ) has improved the prognosis for glioblastoma multiforme patients. However, TMZ resistance may be one of the main reasons why treatment fails. Although this resistance has frequently been linked to the expression of O6-methylguanine-DNA methyltransferase (MGMT) it seems that this enzyme is not the only molecular mechanis...
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Temozolomide Resistance in Glioblastoma Cell Lines: Implication of MGMT, MMR, P-Glycoprotein and CD133 Expression
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TN_cdi_plos_journals_1720193614
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1720193614
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1932-6203
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1932-6203
DOI
10.1371/journal.pone.0140131