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Exclusive Association of p53 Mutation with Super-High Methylation of Tumor Suppressor Genes in the p...

Exclusive Association of p53 Mutation with Super-High Methylation of Tumor Suppressor Genes in the p...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1720193647

Exclusive Association of p53 Mutation with Super-High Methylation of Tumor Suppressor Genes in the p53 Pathway in a Unique Gastric Cancer Phenotype

About this item

Full title

Exclusive Association of p53 Mutation with Super-High Methylation of Tumor Suppressor Genes in the p53 Pathway in a Unique Gastric Cancer Phenotype

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-10, Vol.10 (10), p.e0139902-e0139902

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

A comprehensive search for DNA methylated genes identified candidate tumor suppressor genes that have been proven to be involved in the apoptotic process of the p53 pathway. In this study, we investigated p53 mutation in relation to such epigenetic alteration in primary gastric cancer.
The methylation profiles of the 3 genes: PGP9.5, NMDAR2B, an...

Alternative Titles

Full title

Exclusive Association of p53 Mutation with Super-High Methylation of Tumor Suppressor Genes in the p53 Pathway in a Unique Gastric Cancer Phenotype

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1720193647

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1720193647

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0139902

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