Outer Hair Cell Lateral Wall Structure Constrains the Mobility of Plasma Membrane Proteins
Outer Hair Cell Lateral Wall Structure Constrains the Mobility of Plasma Membrane Proteins
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Author / Creator
Yamashita, Tetsuji , Hakizimana, Pierre , Wu, Siva , Hassan, Ahmed , Jacob, Stefan , Temirov, Jamshid , Fang, Jie , Mellado-Lagarde, Marcia , Gursky, Richard , Horner, Linda , Leibiger, Barbara , Leijon, Sara , Centonze, Victoria E. , Berggren, Per-Olof , Frase, Sharon , Auer, Manfred , Brownell, William E. , Fridberger, Anders , Zuo, Jian and Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Contents
Nature's fastest motors are the cochlear outer hair cells (OHCs). These sensory cells use a membrane protein, Slc26a5 (prestin), to generate mechanical force at high frequencies, which is essential for explaining the exquisite hearing sensitivity of mammalian ears. Previous studies suggest that Slc26a5 continuously diffuses within the membrane, but...
Alternative Titles
Full title
Outer Hair Cell Lateral Wall Structure Constrains the Mobility of Plasma Membrane Proteins
Authors, Artists and Contributors
Author / Creator
Hakizimana, Pierre
Wu, Siva
Hassan, Ahmed
Jacob, Stefan
Temirov, Jamshid
Fang, Jie
Mellado-Lagarde, Marcia
Gursky, Richard
Horner, Linda
Leibiger, Barbara
Leijon, Sara
Centonze, Victoria E.
Berggren, Per-Olof
Frase, Sharon
Auer, Manfred
Brownell, William E.
Fridberger, Anders
Zuo, Jian
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
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Record Identifier
TN_cdi_plos_journals_1720625747
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1720625747
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1005500
