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Discovering Genetic Interactions in Large-Scale Association Studies by Stage-wise Likelihood Ratio T...

Discovering Genetic Interactions in Large-Scale Association Studies by Stage-wise Likelihood Ratio T...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1720625750

Discovering Genetic Interactions in Large-Scale Association Studies by Stage-wise Likelihood Ratio Tests

About this item

Full title

Discovering Genetic Interactions in Large-Scale Association Studies by Stage-wise Likelihood Ratio Tests

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2015-09, Vol.11 (9), p.e1005502-e1005502

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Despite the success of genome-wide association studies in medical genetics, the underlying genetics of many complex diseases remains enigmatic. One plausible reason for this could be the failure to account for the presence of genetic interactions in current analyses. Exhaustive investigations of interactions are typically infeasible because the vas...

Alternative Titles

Full title

Discovering Genetic Interactions in Large-Scale Association Studies by Stage-wise Likelihood Ratio Tests

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1720625750

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1720625750

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1005502