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Deficiency of Calcium-Independent Phospholipase A2 Beta Induces Brain Iron Accumulation through Upre...

Deficiency of Calcium-Independent Phospholipase A2 Beta Induces Brain Iron Accumulation through Upre...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1727647130

Deficiency of Calcium-Independent Phospholipase A2 Beta Induces Brain Iron Accumulation through Upregulation of Divalent Metal Transporter 1

About this item

Full title

Deficiency of Calcium-Independent Phospholipase A2 Beta Induces Brain Iron Accumulation through Upregulation of Divalent Metal Transporter 1

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-10, Vol.10 (10), p.e0141629-e0141629

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Mutations in PLA2G6 have been proposed to be the cause of neurodegeneration with brain iron accumulation type 2. The present study aimed to clarify the mechanism underlying brain iron accumulation during the deficiency of calcium-independent phospholipase A2 beta (iPLA2β), which is encoded by the PLA2G6 gene. Perl's staining with diaminobenzidine e...

Alternative Titles

Full title

Deficiency of Calcium-Independent Phospholipase A2 Beta Induces Brain Iron Accumulation through Upregulation of Divalent Metal Transporter 1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1727647130

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1727647130

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0141629

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