Log in to save to my catalogue

Unc93b Induces Apoptotic Cell Death and Is Cleaved by Host and Enteroviral Proteases

Unc93b Induces Apoptotic Cell Death and Is Cleaved by Host and Enteroviral Proteases

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1727985146

Unc93b Induces Apoptotic Cell Death and Is Cleaved by Host and Enteroviral Proteases

About this item

Full title

Unc93b Induces Apoptotic Cell Death and Is Cleaved by Host and Enteroviral Proteases

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-10, Vol.10 (10), p.e0141383

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Unc93b is an endoplasmic reticulum (ER)-resident transmembrane protein that serves to bind and traffic toll-like receptors (TLRs) from the ER to their appropriate subcellular locations for ligand sensing. Because of its role in TLR trafficking, Unc93b is necessary for an effective innate immune response to coxsackievirus B3 (CVB), a positive-sense...

Alternative Titles

Full title

Unc93b Induces Apoptotic Cell Death and Is Cleaved by Host and Enteroviral Proteases

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1727985146

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1727985146

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0141383

How to access this item