A Phase I Randomized Therapeutic MVA-B Vaccination Improves the Magnitude and Quality of the T Cell...
A Phase I Randomized Therapeutic MVA-B Vaccination Improves the Magnitude and Quality of the T Cell Immune Responses in HIV-1-Infected Subjects on HAART
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Author / Creator
Gómez, Carmen Elena , Perdiguero, Beatriz , García-Arriaza, Juan , Cepeda, Victoria , Sánchez-Sorzano, Carlos Óscar , Mothe, Beatriz , Jiménez, José Luis , Muñoz-Fernández, María Ángeles , Gatell, Jose M. , López Bernaldo de Quirós, Juan Carlos , Brander, Christian , García, Felipe and Esteban, Mariano
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Previous studies suggested that poxvirus-based vaccines might be instrumental in the therapeutic HIV field. A phase I clinical trial was conducted in HIV-1-infected patients on highly active antiretroviral therapy (HAART), with CD4 T cell counts above 450 cells/mm3 and undetectable viremia. Thirty participants were randomized (2:1) to receive eithe...
Alternative Titles
Full title
A Phase I Randomized Therapeutic MVA-B Vaccination Improves the Magnitude and Quality of the T Cell Immune Responses in HIV-1-Infected Subjects on HAART
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Record Identifier
TN_cdi_plos_journals_1731532298
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1731532298
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0141456
