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Knock-Down of the 37kDa/67kDa Laminin Receptor LRP/LR Impedes Telomerase Activity

Knock-Down of the 37kDa/67kDa Laminin Receptor LRP/LR Impedes Telomerase Activity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1731532863

Knock-Down of the 37kDa/67kDa Laminin Receptor LRP/LR Impedes Telomerase Activity

About this item

Full title

Knock-Down of the 37kDa/67kDa Laminin Receptor LRP/LR Impedes Telomerase Activity

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-11, Vol.10 (11), p.e0141618-e0141618

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Cancer has become a major problem worldwide due to its increasing incidence and mortality rates. Both the 37kDa/67kDa laminin receptor (LRP/LR) and telomerase are overexpressed in cancer cells. LRP/LR enhances the invasiveness of cancer cells thereby promoting metastasis, supporting angiogenesis and hampering apoptosis. An essential component of te...

Alternative Titles

Full title

Knock-Down of the 37kDa/67kDa Laminin Receptor LRP/LR Impedes Telomerase Activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1731532863

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1731532863

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0141618

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