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Molecular Insights into the Transmembrane Domain of the Thyrotropin Receptor

Molecular Insights into the Transmembrane Domain of the Thyrotropin Receptor

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1731533091

Molecular Insights into the Transmembrane Domain of the Thyrotropin Receptor

About this item

Full title

Molecular Insights into the Transmembrane Domain of the Thyrotropin Receptor

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-11, Vol.10 (11), p.e0142250

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The thyrotropin receptor (TSHR) is a G protein-coupled receptor (GPCR) that is member of the leucine-rich repeat subfamily (LGR). In the absence of crystal structure, the success of rational design of ligands targeting the receptor internal cavity depends on the quality of the TSHR models built. In this subfamily, transmembrane helices (TM) 2 and 5...

Alternative Titles

Full title

Molecular Insights into the Transmembrane Domain of the Thyrotropin Receptor

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1731533091

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1731533091

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0142250

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