Retinoic Acid Ameliorates Pancreatic Fibrosis and Inhibits the Activation of Pancreatic Stellate Cel...
Retinoic Acid Ameliorates Pancreatic Fibrosis and Inhibits the Activation of Pancreatic Stellate Cells in Mice with Experimental Chronic Pancreatitis via Suppressing the Wnt/β-Catenin Signaling Pathway
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Author / Creator
Xiao, Wenqin , Jiang, Weiliang , Shen, Jie , Yin, Guojian , Fan, Yuting , Wu, Deqing , Qiu, Lei , Yu, Ge , Xing, Miao , Hu, Guoyong , Wang, Xingpeng and Wan, Rong
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Pancreatic fibrosis, a prominent feature of chronic pancreatitis (CP), induces persistent and permanent damage in the pancreas. Pancreatic stellate cells (PSCs) provide a major source of extracellular matrix (ECM) deposition during pancreatic injury, and persistent activation of PSCs plays a vital role in the progression of pancreatic fibrosis. Ret...
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Full title
Retinoic Acid Ameliorates Pancreatic Fibrosis and Inhibits the Activation of Pancreatic Stellate Cells in Mice with Experimental Chronic Pancreatitis via Suppressing the Wnt/β-Catenin Signaling Pathway
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TN_cdi_plos_journals_1732312070
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1732312070
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0141462
