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Tackling Glaucoma from within the Brain: An Unfortunate Interplay of BDNF and TrkB

Tackling Glaucoma from within the Brain: An Unfortunate Interplay of BDNF and TrkB

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1732577126

Tackling Glaucoma from within the Brain: An Unfortunate Interplay of BDNF and TrkB

About this item

Full title

Tackling Glaucoma from within the Brain: An Unfortunate Interplay of BDNF and TrkB

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-11, Vol.10 (11), p.e0142067-e0142067

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

According to the neurotrophin deprivation hypothesis, diminished retrograde delivery of neurotrophic support during an early stage of glaucoma pathogenesis is one of the main triggers that induce retinal ganglion cell (RGC) degeneration. Therefore, interfering with neurotrophic signaling seems an attractive strategy to achieve neuroprotection. Inde...

Alternative Titles

Full title

Tackling Glaucoma from within the Brain: An Unfortunate Interplay of BDNF and TrkB

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1732577126

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1732577126

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0142067

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