Simvastatin Impairs Insulin Secretion by Multiple Mechanisms in MIN6 Cells
Simvastatin Impairs Insulin Secretion by Multiple Mechanisms in MIN6 Cells
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Statins are widely used in the treatment of hypercholesterolemia and are efficient in the prevention of cardiovascular disease. Molecular mechanisms explaining statin-induced impairment in insulin secretion remain largely unknown. In the current study, we show that simvastatin decreased glucose-stimulated insulin secretion in mouse pancreatic MIN6...
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Full title
Simvastatin Impairs Insulin Secretion by Multiple Mechanisms in MIN6 Cells
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TN_cdi_plos_journals_1732577577
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1732577577
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0142902