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Assessment of Interactions between Cisplatin and Two Histone Deacetylase Inhibitors in MCF7, T47D an...

Assessment of Interactions between Cisplatin and Two Histone Deacetylase Inhibitors in MCF7, T47D an...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1734278063

Assessment of Interactions between Cisplatin and Two Histone Deacetylase Inhibitors in MCF7, T47D and MDA-MB-231 Human Breast Cancer Cell Lines – An Isobolographic Analysis

About this item

Full title

Assessment of Interactions between Cisplatin and Two Histone Deacetylase Inhibitors in MCF7, T47D and MDA-MB-231 Human Breast Cancer Cell Lines – An Isobolographic Analysis

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-11, Vol.10 (11), p.e0143013-e0143013

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Histone deacetylase inhibitors (HDIs) are promising anticancer drugs, which inhibit proliferation of a wide variety of cancer cells including breast carcinoma cells. In the present study, we investigated the influence of valproic acid (VPA) and suberoylanilide hydroxamic acid (SAHA, vorinostat), alone or in combination with cisplatin (CDDP) on prol...

Alternative Titles

Full title

Assessment of Interactions between Cisplatin and Two Histone Deacetylase Inhibitors in MCF7, T47D and MDA-MB-231 Human Breast Cancer Cell Lines – An Isobolographic Analysis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1734278063

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1734278063

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0143013

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