Tacrolimus Induces Insulin Resistance and Increases the Glucose Absorption in the Jejunum: A Potenti...
Tacrolimus Induces Insulin Resistance and Increases the Glucose Absorption in the Jejunum: A Potential Mechanism of the Diabetogenic Effects
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Author / Creator
Li, Zhiwei , Sun, Fei , Zhang, Yaohui , Chen, Hao , He, Ningning , Chen, Hui , Song, Penghong , Wang, Yan , Yan, Sheng and Zheng, Shusen
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
The use of the immunosuppressive drug tacrolimus (TAC) is related to new onset diabetes after transplantation. Herein, we examined the effect of intraperitoneal administered TAC on intestinal glucose absorption in mice.
Animals received low, medium, or high dose TAC (0.5, 1, or 5 mg/kg/d, respectively), or 0.9% saline solution (control) for 14 d...
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Full title
Tacrolimus Induces Insulin Resistance and Increases the Glucose Absorption in the Jejunum: A Potential Mechanism of the Diabetogenic Effects
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TN_cdi_plos_journals_1735663801
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1735663801
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0143405
