The Dipeptidyl Peptidase-4 Inhibitor Linagliptin Preserves Endothelial Function in Mesenteric Arteri...
The Dipeptidyl Peptidase-4 Inhibitor Linagliptin Preserves Endothelial Function in Mesenteric Arteries from Type 1 Diabetic Rats without Decreasing Plasma Glucose
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United States: Public Library of Science
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English
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United States: Public Library of Science
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The aim of the study was to investigate the effect of the DPP-4 inhibitor linagliptin on the mechanism(s) of endothelium-dependent relaxation in mesenteric arteries from STZ-induced diabetic rats. Both normal and diabetic animals received linagliptin (2 mg/kg) daily by oral gavage for a period of 4 weeks. To measure superoxide generation in mesente...
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Full title
The Dipeptidyl Peptidase-4 Inhibitor Linagliptin Preserves Endothelial Function in Mesenteric Arteries from Type 1 Diabetic Rats without Decreasing Plasma Glucose
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TN_cdi_plos_journals_1738003181
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1738003181
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0143941
