A Synthetic Lethality Screen Using a Focused siRNA Library to Identify Sensitizers to Dasatinib Ther...
A Synthetic Lethality Screen Using a Focused siRNA Library to Identify Sensitizers to Dasatinib Therapy for the Treatment of Epithelial Ovarian Cancer
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Molecular targeted therapies have been the focus of recent clinical trials for the treatment of patients with recurrent epithelial ovarian cancer (EOC). The majority have not fared well as monotherapies for improving survival of these patients. Poor bioavailability, lack of predictive biomarkers, and the presence of multiple survival pathways can a...
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Full title
A Synthetic Lethality Screen Using a Focused siRNA Library to Identify Sensitizers to Dasatinib Therapy for the Treatment of Epithelial Ovarian Cancer
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TN_cdi_plos_journals_1739314867
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1739314867
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0144126
