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Comparison of Gene Expression by Sheep and Human Blood Stimulated with the TLR4 Agonists Lipopolysac...

Comparison of Gene Expression by Sheep and Human Blood Stimulated with the TLR4 Agonists Lipopolysac...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1746586300

Comparison of Gene Expression by Sheep and Human Blood Stimulated with the TLR4 Agonists Lipopolysaccharide and Monophosphoryl Lipid A

About this item

Full title

Comparison of Gene Expression by Sheep and Human Blood Stimulated with the TLR4 Agonists Lipopolysaccharide and Monophosphoryl Lipid A

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-12, Vol.10 (12), p.e0144345-e0144345

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Animal models that mimic human biology are important for successful translation of basic science discoveries into the clinical practice. Recent studies in rodents have demonstrated the efficacy of TLR4 agonists as immunomodulators in models of infection. However, rodent models have been criticized for not mimicking important characteristics of the...

Alternative Titles

Full title

Comparison of Gene Expression by Sheep and Human Blood Stimulated with the TLR4 Agonists Lipopolysaccharide and Monophosphoryl Lipid A

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1746586300

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1746586300

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0144345

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