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MASP-1 Induced Clotting – The First Model of Prothrombin Activation by MASP-1

MASP-1 Induced Clotting – The First Model of Prothrombin Activation by MASP-1

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1746865075

MASP-1 Induced Clotting – The First Model of Prothrombin Activation by MASP-1

About this item

Full title

MASP-1 Induced Clotting – The First Model of Prothrombin Activation by MASP-1

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-12, Vol.10 (12), p.e0144633-e0144633

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Mannan-binding lectin-associated serine protease-1 (MASP-1), a protein of the complement lectin pathway, resembles thrombin in terms of structural features and substrate specificity. Due to its interplay with several coagulation factors, it has the ability to induce fibrin clot formation independent of the usual coagulation activation pathways. We...

Alternative Titles

Full title

MASP-1 Induced Clotting – The First Model of Prothrombin Activation by MASP-1

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1746865075

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1746865075

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0144633

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