Pharmacological Inhibition of O-GlcNAcase Does Not Increase Sensitivity of Glucocorticoid Receptor-M...
Pharmacological Inhibition of O-GlcNAcase Does Not Increase Sensitivity of Glucocorticoid Receptor-Mediated Transrepression
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Glucocorticoid signaling regulates target genes by multiple mechanisms, including the repression of transcriptional activities of nuclear factor κ-light-chain-enhancer of activated B cells (NF-κB) though direct protein-protein interactions and subsequent O-GlcNAcylation of RNA polymerase II (pol II). Recent studies have shown that overexpression of...
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Pharmacological Inhibition of O-GlcNAcase Does Not Increase Sensitivity of Glucocorticoid Receptor-Mediated Transrepression
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TN_cdi_plos_journals_1749178768
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1749178768
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0145151
