Protumoral TSP50 Regulates Macrophage Activities and Polarization via Production of TNF-α and IL-1β,...
Protumoral TSP50 Regulates Macrophage Activities and Polarization via Production of TNF-α and IL-1β, and Activation of the NF-κB Signaling Pathway
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Testes-specific protease 50 (TSP50) is abnormally overexpressed in many kinds of cancers and promotes cell proliferation and migration. However, whether TSP50 can influence the tumor microenvironment, especially the function of immune cells in the microenvironment, remains largely unknown. We demonstrated that exposure to the conditioned medium fro...
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Protumoral TSP50 Regulates Macrophage Activities and Polarization via Production of TNF-α and IL-1β, and Activation of the NF-κB Signaling Pathway
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TN_cdi_plos_journals_1750199386
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1750199386
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0145095
