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Molecular Dynamics Simulation Reveals Correlated Inter-Lobe Motion in Protein Lysine Methyltransfera...

Molecular Dynamics Simulation Reveals Correlated Inter-Lobe Motion in Protein Lysine Methyltransfera...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1752582946

Molecular Dynamics Simulation Reveals Correlated Inter-Lobe Motion in Protein Lysine Methyltransferase SMYD2

About this item

Full title

Molecular Dynamics Simulation Reveals Correlated Inter-Lobe Motion in Protein Lysine Methyltransferase SMYD2

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-12, Vol.10 (12), p.e0145758-e0145758

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

SMYD proteins are an exciting field of study as they are linked to many types of cancer-related pathways. Cardiac and skeletal muscle development and function also depend on SMYD proteins opening a possible avenue for cardiac-related treatment. Previous crystal structure studies have revealed that this special class of protein lysine methyltransfer...

Alternative Titles

Full title

Molecular Dynamics Simulation Reveals Correlated Inter-Lobe Motion in Protein Lysine Methyltransferase SMYD2

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1752582946

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1752582946

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0145758

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