BAD, a Proapoptotic Protein, Escapes ERK/RSK Phosphorylation in Deguelin and siRNA-Treated HeLa Cell...
BAD, a Proapoptotic Protein, Escapes ERK/RSK Phosphorylation in Deguelin and siRNA-Treated HeLa Cells
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Author / Creator
Hafeez, Samra , Urooj, Mahwish , Saleem, Shamiala , Gillani, Zeeshan , Shaheen, Sumaira , Qazi, Mahmood Husain , Naseer, Muhammad Imran , Iqbal, Zafar , Ansari, Shakeel Ahmed , Haque, Absarul , Asif, Muhammad , Mir, Manzoor Ahmad , Ali, Ashraf , Pushparaj, Peter Natesan , Jamal, Mohammad Sarwar and Rasool, Mahmood
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
This study has been undertaken to explore the therapeutic effects of deguelin and specific siRNAs in HeLa cells. The data provided clearly show the silencing of ERK 1/2 with siRNAs and inhibition of ERK1/2 with deguelin treatment in HeLa cells. Additionally, we are providing information that deguelin binds directly to anti-apoptotic Bcl-2, Bcl-xl a...
Alternative Titles
Full title
BAD, a Proapoptotic Protein, Escapes ERK/RSK Phosphorylation in Deguelin and siRNA-Treated HeLa Cells
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Record Identifier
TN_cdi_plos_journals_1755065511
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1755065511
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0145780
