Osteoprotegerin Regulates Pancreatic β-Cell Homeostasis upon Microbial Invasion
Osteoprotegerin Regulates Pancreatic β-Cell Homeostasis upon Microbial Invasion
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Osteoprotegerin (OPG), a decoy receptor for receptor activator of NF-κB ligand (RANKL), antagonizes RANKL's osteoclastogenic function in bone. We previously demonstrated that systemic administration of lipopolysaccharide (LPS) to mice elevates OPG levels and reduces RANKL levels in peripheral blood. Here, we show that mice infected with Salmonella,...
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Osteoprotegerin Regulates Pancreatic β-Cell Homeostasis upon Microbial Invasion
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TN_cdi_plos_journals_1755795414
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1755795414
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0146544
