A Novel Triazolopyridine-Based Spleen Tyrosine Kinase Inhibitor That Arrests Joint Inflammation
A Novel Triazolopyridine-Based Spleen Tyrosine Kinase Inhibitor That Arrests Joint Inflammation
About this item
Full title
Author / Creator
Ferguson, Gregory D. , Delgado, Mercedes , Plantevin-Krenitsky, Veronique , Jensen-Pergakes, Kristen , Bates, R. J. , Torres, Sanaa , Celeridad, Maria , Brown, Heather , Burnett, Kelven , Nadolny, Lisa , Tehrani, Lida , Packard, Garrick , Pagarigan, Barbra , Haelewyn, Jason , Nguyen, Trish , Xu, Li , Tang, Yang , Hickman, Matthew , Baculi, Frans , Pierce, Steven , Miyazawa, Keiji , Jackson, Pilgrim , Chamberlain, Philip , LeBrun, Laurie , Xie, Weilin , Bennett, Brydon , Blease, Kate and Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Autoantibodies and the immunoreceptors to which they bind can contribute to the pathogenesis of autoimmune diseases such as rheumatoid arthritis (RA). Spleen Tyrosine Kinase (Syk) is a non-receptor tyrosine kinase with a central role in immunoreceptor (FcR) signaling and immune cell functionality. Syk kinase inhibitors have activity in antibody-dep...
Alternative Titles
Full title
A Novel Triazolopyridine-Based Spleen Tyrosine Kinase Inhibitor That Arrests Joint Inflammation
Authors, Artists and Contributors
Author / Creator
Delgado, Mercedes
Plantevin-Krenitsky, Veronique
Jensen-Pergakes, Kristen
Bates, R. J.
Torres, Sanaa
Celeridad, Maria
Brown, Heather
Burnett, Kelven
Nadolny, Lisa
Tehrani, Lida
Packard, Garrick
Pagarigan, Barbra
Haelewyn, Jason
Nguyen, Trish
Xu, Li
Tang, Yang
Hickman, Matthew
Baculi, Frans
Pierce, Steven
Miyazawa, Keiji
Jackson, Pilgrim
Chamberlain, Philip
LeBrun, Laurie
Xie, Weilin
Bennett, Brydon
Blease, Kate
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1756065960
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1756065960
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0145705
