Candida albicans Targets a Lipid Raft/Dectin-1 Platform to Enter Human Monocytes and Induce Antigen...
Candida albicans Targets a Lipid Raft/Dectin-1 Platform to Enter Human Monocytes and Induce Antigen Specific T Cell Responses
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Several pathogens have been described to enter host cells via cholesterol-enriched membrane lipid raft microdomains. We found that disruption of lipid rafts by the cholesterol-extracting agent methyl-β-cyclodextrin or by the cholesterol-binding antifungal drug Amphotericin B strongly impairs the uptake of the fungal pathogen Candida albicans by hum...
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Candida albicans Targets a Lipid Raft/Dectin-1 Platform to Enter Human Monocytes and Induce Antigen Specific T Cell Responses
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TN_cdi_plos_journals_1756962910
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1756962910
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0142531