Wnt5a Deficiency Leads to Anomalies in Ureteric Tree Development, Tubular Epithelial Cell Organizati...
Wnt5a Deficiency Leads to Anomalies in Ureteric Tree Development, Tubular Epithelial Cell Organization and Basement Membrane Integrity Pointing to a Role in Kidney Collecting Duct Patterning
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Pietilä, Ilkka , Prunskaite-Hyyryläinen, Renata , Kaisto, Susanna , Tika, Elisavet , van Eerde, Albertien M , Salo, Antti M , Garma, Leonardo , Miinalainen, Ilkka , Feitz, Wout F , Bongers, Ernie M H F , Juffer, André , Knoers, Nine V A M , Renkema, Kirsten Y , Myllyharju, Johanna and Vainio, Seppo J
Publisher
United States: Public Library of Science
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English
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United States: Public Library of Science
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Contents
The Wnts can be considered as candidates for the Congenital Anomaly of Kidney and Urinary Tract, CAKUT diseases since they take part in the control of kidney organogenesis. Of them Wnt5a is expressed in ureteric bud (UB) and its deficiency leads to duplex collecting system (13/90) uni- or bilateral kidney agenesis (10/90), hypoplasia with altered p...
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Full title
Wnt5a Deficiency Leads to Anomalies in Ureteric Tree Development, Tubular Epithelial Cell Organization and Basement Membrane Integrity Pointing to a Role in Kidney Collecting Duct Patterning
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TN_cdi_plos_journals_1758978176
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1758978176
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0147171