Loss of Endothelial Barrier in Marfan Mice (mgR/mgR) Results in Severe Inflammation after Adenoviral...
Loss of Endothelial Barrier in Marfan Mice (mgR/mgR) Results in Severe Inflammation after Adenoviral Gene Therapy
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Marfan syndrome is an autosomal dominant inherited disorder of connective tissue. The vascular complications of Marfan syndrome have the biggest impact on life expectancy. The aorta of Marfan patients reveals degradation of elastin layers caused by increased proteolytic activity of matrix metalloproteinases (MMPs). In this study we performed adenov...
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Loss of Endothelial Barrier in Marfan Mice (mgR/mgR) Results in Severe Inflammation after Adenoviral Gene Therapy
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TN_cdi_plos_journals_1762350224
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1762350224
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0148012