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Serotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension

Serotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1764342583

Serotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension

About this item

Full title

Serotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension

Publisher

United States: Public Library of Science

Journal title

PloS one, 2016-02, Vol.11 (2), p.e0148657-e0148657

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Serotonergic anorexigens are the primary pharmacologic risk factor associated with pulmonary arterial hypertension (PAH), and the resulting PAH is clinically indistinguishable from the heritable form of disease, associated with BMPR2 mutations. Both BMPR2 mutation and agonists to the serotonin receptor HTR2B have been shown to cause activation of S...

Alternative Titles

Full title

Serotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1764342583

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1764342583

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0148657

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