Serotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension
Serotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Contents
Serotonergic anorexigens are the primary pharmacologic risk factor associated with pulmonary arterial hypertension (PAH), and the resulting PAH is clinically indistinguishable from the heritable form of disease, associated with BMPR2 mutations. Both BMPR2 mutation and agonists to the serotonin receptor HTR2B have been shown to cause activation of S...
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Serotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension
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TN_cdi_plos_journals_1764342583
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1764342583
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0148657