Colon Cancer Tumorigenesis Initiated by the H1047R Mutant PI3K
Colon Cancer Tumorigenesis Initiated by the H1047R Mutant PI3K
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The phosphoinositide 3-kinase (PI3K) signaling pathway is critical for multiple important cellular functions, and is one of the most commonly altered pathways in human cancers. We previously developed a mouse model in which colon cancers were initiated by a dominant active PI3K p110-p85 fusion protein. In that model, well-differentiated mucinous ad...
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Full title
Colon Cancer Tumorigenesis Initiated by the H1047R Mutant PI3K
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TN_cdi_plos_journals_1764342681
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1764342681
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0148730
