Systems-Wide Prediction of Enzyme Promiscuity Reveals a New Underground Alternative Route for Pyrido...
Systems-Wide Prediction of Enzyme Promiscuity Reveals a New Underground Alternative Route for Pyridoxal 5’-Phosphate Production in E. coli
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Recent insights suggest that non-specific and/or promiscuous enzymes are common and active across life. Understanding the role of such enzymes is an important open question in biology. Here we develop a genome-wide method, PROPER, that uses a permissive PSI-BLAST approach to predict promiscuous activities of metabolic genes. Enzyme promiscuity is t...
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Systems-Wide Prediction of Enzyme Promiscuity Reveals a New Underground Alternative Route for Pyridoxal 5’-Phosphate Production in E. coli
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TN_cdi_plos_journals_1764351722
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1764351722
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1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1004705
