GDF-15 Is Elevated in Children with Mitochondrial Diseases and Is Induced by Mitochondrial Dysfuncti...
GDF-15 Is Elevated in Children with Mitochondrial Diseases and Is Induced by Mitochondrial Dysfunction
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Author / Creator
Montero, Raquel , Yubero, Delia , Villarroya, Joan , Henares, Desiree , Jou, Cristina , Rodríguez, Maria Angeles , Ramos, Federico , Nascimento, Andrés , Ortez, Carlos Ignacio , Campistol, Jaume , Perez-Dueñas, Belen , O'Callaghan, Mar , Pineda, Mercedes , Garcia-Cazorla, Angeles , Oferil, Jaume Colomer , Montoya, Julio , Ruiz-Pesini, Eduardo , Emperador, Sonia , Meznaric, Marija , Campderros, Laura , Kalko, Susana G. , Villarroya, Francesc , Artuch, Rafael and Jimenez-Mallebrera, Cecilia
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
We previously described increased levels of growth and differentiation factor 15 (GDF-15) in skeletal muscle and serum of patients with mitochondrial diseases. Here we evaluated GDF-15 as a biomarker for mitochondrial diseases affecting children and compared it to fibroblast-growth factor 21 (FGF-21). To investigate the mechanism of GDF-15 inductio...
Alternative Titles
Full title
GDF-15 Is Elevated in Children with Mitochondrial Diseases and Is Induced by Mitochondrial Dysfunction
Authors, Artists and Contributors
Author / Creator
Yubero, Delia
Villarroya, Joan
Henares, Desiree
Jou, Cristina
Rodríguez, Maria Angeles
Ramos, Federico
Nascimento, Andrés
Ortez, Carlos Ignacio
Campistol, Jaume
Perez-Dueñas, Belen
O'Callaghan, Mar
Pineda, Mercedes
Garcia-Cazorla, Angeles
Oferil, Jaume Colomer
Montoya, Julio
Ruiz-Pesini, Eduardo
Emperador, Sonia
Meznaric, Marija
Campderros, Laura
Kalko, Susana G.
Villarroya, Francesc
Artuch, Rafael
Jimenez-Mallebrera, Cecilia
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Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1764705920
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1764705920
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0148709