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GDF-15 Is Elevated in Children with Mitochondrial Diseases and Is Induced by Mitochondrial Dysfuncti...

GDF-15 Is Elevated in Children with Mitochondrial Diseases and Is Induced by Mitochondrial Dysfuncti...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1764705920

GDF-15 Is Elevated in Children with Mitochondrial Diseases and Is Induced by Mitochondrial Dysfunction

About this item

Full title

GDF-15 Is Elevated in Children with Mitochondrial Diseases and Is Induced by Mitochondrial Dysfunction

Publisher

United States: Public Library of Science

Journal title

PloS one, 2016-02, Vol.11 (2), p.e0148709-e0148709

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

We previously described increased levels of growth and differentiation factor 15 (GDF-15) in skeletal muscle and serum of patients with mitochondrial diseases. Here we evaluated GDF-15 as a biomarker for mitochondrial diseases affecting children and compared it to fibroblast-growth factor 21 (FGF-21). To investigate the mechanism of GDF-15 inductio...

Alternative Titles

Full title

GDF-15 Is Elevated in Children with Mitochondrial Diseases and Is Induced by Mitochondrial Dysfunction

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1764705920

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1764705920

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0148709

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