Carvedilol Improves Inflammatory Response, Oxidative Stress and Fibrosis in the Alcohol-Induced Live...
Carvedilol Improves Inflammatory Response, Oxidative Stress and Fibrosis in the Alcohol-Induced Liver Injury in Rats by Regulating Kuppfer Cells and Hepatic Stellate Cells
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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To evaluate the anti-inflammatory, anti-oxidant and antifibrotic effects of carvedilol (CARV) in rats with ethanol-induced liver injury.
Liver injury was induced by gavage administration of alcohol (7 g/kg) for 28 consecutive days. Eighty Wistar rats were pretreated with oral CARV at 1, 3, or 5 mg/kg or with saline 1 h before exposure to alcohol...
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Full title
Carvedilol Improves Inflammatory Response, Oxidative Stress and Fibrosis in the Alcohol-Induced Liver Injury in Rats by Regulating Kuppfer Cells and Hepatic Stellate Cells
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TN_cdi_plos_journals_1771236512
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1771236512
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0148868
