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Identification of Adjuvantic Activity of Amphotericin B in a Novel, Multiplexed, Poly-TLR/NLR High-T...

Identification of Adjuvantic Activity of Amphotericin B in a Novel, Multiplexed, Poly-TLR/NLR High-T...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1771271358

Identification of Adjuvantic Activity of Amphotericin B in a Novel, Multiplexed, Poly-TLR/NLR High-Throughput Screen

About this item

Full title

Identification of Adjuvantic Activity of Amphotericin B in a Novel, Multiplexed, Poly-TLR/NLR High-Throughput Screen

Publisher

United States: Public Library of Science

Journal title

PloS one, 2016-02, Vol.11 (2), p.e0149848-e0149848

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Small-molecule agonists have been identified for TLR7, TLR8, TLR4 and TLR2 thus far, and chemotypes other than those of canonical ligands are yet to be explored for a number of innate immune receptors. The discovery of novel immunostimulatory molecules would enhance the repertoire of tools available for interrogating innate immune effector mechanis...

Alternative Titles

Full title

Identification of Adjuvantic Activity of Amphotericin B in a Novel, Multiplexed, Poly-TLR/NLR High-Throughput Screen

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1771271358

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1771271358

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0149848

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