SMN Protein Can Be Reliably Measured in Whole Blood with an Electrochemiluminescence (ECL) Immunoass...
SMN Protein Can Be Reliably Measured in Whole Blood with an Electrochemiluminescence (ECL) Immunoassay: Implications for Clinical Trials
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Spinal muscular atrophy (SMA) is caused by defects in the survival motor neuron 1 (SMN1) gene that encodes survival motor neuron (SMN) protein. The majority of therapeutic approaches currently in clinical development for SMA aim to increase SMN protein expression and there is a need for sensitive methods able to quantify increases in SMN protein le...
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Full title
SMN Protein Can Be Reliably Measured in Whole Blood with an Electrochemiluminescence (ECL) Immunoassay: Implications for Clinical Trials
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TN_cdi_plos_journals_1771446356
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1771446356
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0150640
