Identification of Novel Candidate Genes for Early-Onset Colorectal Cancer Susceptibility
Identification of Novel Candidate Genes for Early-Onset Colorectal Cancer Susceptibility
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Author / Creator
de Voer, Richarda M , Hahn, Marc-Manuel , Weren, Robbert D A , Mensenkamp, Arjen R , Gilissen, Christian , van Zelst-Stams, Wendy A , Spruijt, Liesbeth , Kets, C Marleen , Zhang, Junxiao , Venselaar, Hanka , Vreede, Lilian , Schubert, Nil , Tychon, Marloes , Derks, Ronny , Schackert, Hans K , Geurts van Kessel, Ad , Hoogerbrugge, Nicoline , Ligtenberg, Marjolijn J L and Kuiper, Roland P
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Approximately 25-30% of colorectal cancer (CRC) cases are expected to result from a genetic predisposition, but in only 5-10% of these cases highly penetrant germline mutations are found. The remaining CRC heritability is still unexplained, and may be caused by a hitherto-undefined set of rare variants with a moderately penetrant risk. Here we aime...
Alternative Titles
Full title
Identification of Novel Candidate Genes for Early-Onset Colorectal Cancer Susceptibility
Authors, Artists and Contributors
Author / Creator
Hahn, Marc-Manuel
Weren, Robbert D A
Mensenkamp, Arjen R
Gilissen, Christian
van Zelst-Stams, Wendy A
Spruijt, Liesbeth
Kets, C Marleen
Zhang, Junxiao
Venselaar, Hanka
Vreede, Lilian
Schubert, Nil
Tychon, Marloes
Derks, Ronny
Schackert, Hans K
Geurts van Kessel, Ad
Hoogerbrugge, Nicoline
Ligtenberg, Marjolijn J L
Kuiper, Roland P
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Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1773769555
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1773769555
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1005880
