Protein Kinase A Activation Promotes Cancer Cell Resistance to Glucose Starvation and Anoikis
Protein Kinase A Activation Promotes Cancer Cell Resistance to Glucose Starvation and Anoikis
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Author / Creator
Palorini, Roberta , Votta, Giuseppina , Pirola, Yuri , De Vitto, Humberto , De Palma, Sara , Airoldi, Cristina , Vasso, Michele , Ricciardiello, Francesca , Lombardi, Pietro Paolo , Cirulli, Claudia , Rizzi, Raffaella , Nicotra, Francesco , Hiller, Karsten , Gelfi, Cecilia , Alberghina, Lilia and Chiaradonna, Ferdinando
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Cancer cells often rely on glycolysis to obtain energy and support anabolic growth. Several studies showed that glycolytic cells are susceptible to cell death when subjected to low glucose availability or to lack of glucose. However, some cancer cells, including glycolytic ones, can efficiently acquire higher tolerance to glucose depletion, leading...
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Full title
Protein Kinase A Activation Promotes Cancer Cell Resistance to Glucose Starvation and Anoikis
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TN_cdi_plos_journals_1781391978
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1781391978
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1005931
