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Mutational Profiles Reveal an Aberrant TGF-β-CEA Regulated Pathway in Colon Adenomas

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Mutational Profiles Reveal an Aberrant TGF-β-CEA Regulated Pathway in Colon Adenomas

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1783594554

Mutational Profiles Reveal an Aberrant TGF-β-CEA Regulated Pathway in Colon Adenomas

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United States: Public Library of Science

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Contents

Mutational processes and signatures that drive early tumorigenesis are centrally important for early cancer prevention. Yet, to date, biomarkers and risk factors for polyps (adenomas) that inordinately and rapidly develop into colon cancer remain poorly defined. Here, we describe surprisingly high mutational profiles through whole-genome sequence (...

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Mutational Profiles Reveal an Aberrant TGF-β-CEA Regulated Pathway in Colon Adenomas

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TN_cdi_plos_journals_1783594554

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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1783594554

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ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0153933

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