Conventional and Regulatory CD4+ T Cells That Share Identical TCRs Are Derived from Common Clones
Conventional and Regulatory CD4+ T Cells That Share Identical TCRs Are Derived from Common Clones
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Results from studies comparing the diversity and specificity of the TCR repertoires expressed by conventional (Tconv) and regulatory (Treg) CD4+ T cell have varied depending on the experimental system employed. We developed a new model in which T cells express a single fixed TCRα chain, randomly rearranged endogenous TCRβ chains, and a Foxp3-GFP re...
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Full title
Conventional and Regulatory CD4+ T Cells That Share Identical TCRs Are Derived from Common Clones
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TN_cdi_plos_journals_1783594908
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1783594908
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0153705
