An Arginine Deprivation Response Pathway Is Induced in Leishmania during Macrophage Invasion
An Arginine Deprivation Response Pathway Is Induced in Leishmania during Macrophage Invasion
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Amino acid sensing is an intracellular function that supports nutrient homeostasis, largely through controlled release of amino acids from lysosomal pools. The intracellular pathogen Leishmania resides and proliferates within human macrophage phagolysosomes. Here we describe a new pathway in Leishmania that specifically senses the extracellular lev...
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An Arginine Deprivation Response Pathway Is Induced in Leishmania during Macrophage Invasion
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TN_cdi_plos_journals_1789548633
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1789548633
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1005494
