Excessive Osteocytic Fgf23 Secretion Contributes to Pyrophosphate Accumulation and Mineralization De...
Excessive Osteocytic Fgf23 Secretion Contributes to Pyrophosphate Accumulation and Mineralization Defect in Hyp Mice
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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X-linked hypophosphatemia (XLH) is the most frequent form of inherited rickets in humans caused by mutations in the phosphate-regulating gene with homologies to endopeptidases on the X-chromosome (PHEX). Hyp mice, a murine homologue of XLH, are characterized by hypophosphatemia, inappropriately low serum vitamin D levels, increased serum fibroblast...
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Full title
Excessive Osteocytic Fgf23 Secretion Contributes to Pyrophosphate Accumulation and Mineralization Defect in Hyp Mice
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TN_cdi_plos_journals_1789551505
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1789551505
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ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.1002427
