Low Mutation Burden in Ovarian Cancer May Limit the Utility of Neoantigen-Targeted Vaccines
Low Mutation Burden in Ovarian Cancer May Limit the Utility of Neoantigen-Targeted Vaccines
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Due to advances in sequencing technology, somatically mutated cancer antigens, or neoantigens, are now readily identifiable and have become compelling targets for immunotherapy. In particular, neoantigen-targeted vaccines have shown promise in several pre-clinical and clinical studies. However, to date, neoantigen-targeted vaccine studies have invo...
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Low Mutation Burden in Ovarian Cancer May Limit the Utility of Neoantigen-Targeted Vaccines
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TN_cdi_plos_journals_1789766524
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1789766524
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0155189
