Efficacy of the Quorum Sensing Inhibitor FS10 Alone and in Combination with Tigecycline in an Animal...
Efficacy of the Quorum Sensing Inhibitor FS10 Alone and in Combination with Tigecycline in an Animal Model of Staphylococcal Infected Wound
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United States: Public Library of Science
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English
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United States: Public Library of Science
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In staphylococci, quorum sensing regulates both biofilm formation and toxin production, moreover it has been demonstrated to be inhibited by RNAIII inhibiting peptide (RIP). Aim our study was to evaluate the in vitro activity and its in vivo efficacy of the combined administration of FS10, a novel RIP derivative, and tigecycline in an animal model...
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Full title
Efficacy of the Quorum Sensing Inhibitor FS10 Alone and in Combination with Tigecycline in an Animal Model of Staphylococcal Infected Wound
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TN_cdi_plos_journals_1793570990
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1793570990
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0151956
