A Functionally Superior Second-Generation Vector Expressing an Aurora Kinase-A-Specific T-Cell Recep...
A Functionally Superior Second-Generation Vector Expressing an Aurora Kinase-A-Specific T-Cell Receptor for Anti-Leukaemia Adoptive Immunotherapy
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Aurora Kinase A is a cancer-associated protein normally involved in the regulation of mitosis. Being over-expressed in a range of cancers, it is a suitable target for cell-based immunotherapy. Gene transfer of T-cell receptor sequences cognisant of HLA-A*0201-restricted Aurora Kinase A antigen has previously been shown to transfer specific immunore...
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Full title
A Functionally Superior Second-Generation Vector Expressing an Aurora Kinase-A-Specific T-Cell Receptor for Anti-Leukaemia Adoptive Immunotherapy
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TN_cdi_plos_journals_1794513206
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1794513206
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0156896
