Targeted Delivery of Deoxycytidine Kinase to Her2-Positive Cells Enhances the Efficacy of the Nucleo...
Targeted Delivery of Deoxycytidine Kinase to Her2-Positive Cells Enhances the Efficacy of the Nucleoside Analog Fludarabine
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Cytotoxic drugs, such as nucleoside analogs and toxins, commonly suffer from off-target effects. One approach to mitigate this problem is to deliver the cytotoxic drug selectively to the intended site. While for toxins this can be achieved by conjugating the cell-killing moiety to a targeting moiety, it is not an option for nucleoside analogs, whic...
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Full title
Targeted Delivery of Deoxycytidine Kinase to Her2-Positive Cells Enhances the Efficacy of the Nucleoside Analog Fludarabine
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TN_cdi_plos_journals_1795488739
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1795488739
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0157114
