Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocy...
Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling
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Author / Creator
Abiega, Oihane , Beccari, Sol , Diaz-Aparicio, Irune , Nadjar, Agnes , Layé, Sophie , Leyrolle, Quentin , Gómez-Nicola, Diego , Domercq, María , Pérez-Samartín, Alberto , Sánchez-Zafra, Víctor , Paris, Iñaki , Valero, Jorge , Savage, Julie C. , Hui, Chin-Wai , Tremblay, Marie-Ève , Deudero, Juan J. P. , Brewster, Amy L. , Anderson, Anne E. , Zaldumbide, Laura , Galbarriatu, Lara , Marinas, Ainhoa , Vivanco, Maria dM , Matute, Carlos , Maletic-Savatic, Mirjana , Encinas, Juan M. and Sierra, Amanda
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Phagocytosis is essential to maintain tissue homeostasis in a large number of inflammatory and autoimmune diseases, but its role in the diseased brain is poorly explored. Recent findings suggest that in the adult hippocampal neurogenic niche, where the excess of newborn cells undergo apoptosis in physiological conditions, phagocytosis is efficientl...
Alternative Titles
Full title
Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling
Authors, Artists and Contributors
Author / Creator
Beccari, Sol
Diaz-Aparicio, Irune
Nadjar, Agnes
Layé, Sophie
Leyrolle, Quentin
Gómez-Nicola, Diego
Domercq, María
Pérez-Samartín, Alberto
Sánchez-Zafra, Víctor
Paris, Iñaki
Valero, Jorge
Savage, Julie C.
Hui, Chin-Wai
Tremblay, Marie-Ève
Deudero, Juan J. P.
Brewster, Amy L.
Anderson, Anne E.
Zaldumbide, Laura
Galbarriatu, Lara
Marinas, Ainhoa
Vivanco, Maria dM
Matute, Carlos
Maletic-Savatic, Mirjana
Encinas, Juan M.
Sierra, Amanda
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1797504399
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1797504399
Other Identifiers
ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.1002466
