Model Predicts That MKP1 and TAB1 Regulate p38α Nuclear Pulse and Its Basal Activity through Positiv...
Model Predicts That MKP1 and TAB1 Regulate p38α Nuclear Pulse and Its Basal Activity through Positive and Negative Feedback Loops in Response to IL-1
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Interleukin-1 mediates inflammation and stress response through nuclear activity of p38α. Although IL-1 receptor is not degraded, p38α activation is transient. IL-1 also causes cell migration and EMT by modulating cell-cell junctions. Although molecules involved in p38 activation are known, mechanism of the transient nuclear response and its basal...
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Full title
Model Predicts That MKP1 and TAB1 Regulate p38α Nuclear Pulse and Its Basal Activity through Positive and Negative Feedback Loops in Response to IL-1
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TN_cdi_plos_journals_1797683276
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1797683276
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0157572
