Interleukin-6 Induces Vascular Endothelial Growth Factor-C Expression via Src-FAK-STAT3 Signaling in...
Interleukin-6 Induces Vascular Endothelial Growth Factor-C Expression via Src-FAK-STAT3 Signaling in Lymphatic Endothelial Cells
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Elevated serum interleukin-6 (IL-6) levels correlates with tumor grade and poor prognosis in cancer patients. IL-6 has been shown to promote tumor lymphangiogenesis through vascular endothelial growth factor-C (VEGF-C) induction in tumor cells. We recently showed that IL-6 also induced VEGF-C expression in lymphatic endothelial cells (LECs). Howeve...
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Full title
Interleukin-6 Induces Vascular Endothelial Growth Factor-C Expression via Src-FAK-STAT3 Signaling in Lymphatic Endothelial Cells
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TN_cdi_plos_journals_1802192463
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1802192463
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0158839
