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The ESX-5 System of Pathogenic Mycobacteria Is Involved In Capsule Integrity and Virulence through I...

The ESX-5 System of Pathogenic Mycobacteria Is Involved In Capsule Integrity and Virulence through I...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1805475478

The ESX-5 System of Pathogenic Mycobacteria Is Involved In Capsule Integrity and Virulence through Its Substrate PPE10

About this item

Full title

The ESX-5 System of Pathogenic Mycobacteria Is Involved In Capsule Integrity and Virulence through Its Substrate PPE10

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2016-06, Vol.12 (6), p.e1005696-e1005696

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Mycobacteria produce a capsule layer, which consists of glycan-like polysaccharides and a number of specific proteins. In this study, we show that, in slow-growing mycobacteria, the type VII secretion system ESX-5 plays a major role in the integrity and stability of the capsule. We have identified PPE10 as the ESX-5 substrate responsible for this e...

Alternative Titles

Full title

The ESX-5 System of Pathogenic Mycobacteria Is Involved In Capsule Integrity and Virulence through Its Substrate PPE10

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1805475478

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1805475478

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1005696

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