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Neuron-Specific Deletion of the Nf2 Tumor Suppressor Impairs Functional Nerve Regeneration

Neuron-Specific Deletion of the Nf2 Tumor Suppressor Impairs Functional Nerve Regeneration

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1807560941

Neuron-Specific Deletion of the Nf2 Tumor Suppressor Impairs Functional Nerve Regeneration

About this item

Full title

Neuron-Specific Deletion of the Nf2 Tumor Suppressor Impairs Functional Nerve Regeneration

Publisher

United States: Public Library of Science

Journal title

PloS one, 2016-07, Vol.11 (7), p.e0159718-e0159718

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

In contrast to axons of the central nervous system (CNS), axons of the peripheral nervous system (PNS) show better, but still incomplete and often slow regeneration following injury. The tumor suppressor protein merlin, mutated in the hereditary tumor syndrome Neurofibromatosis type 2 (NF2), has recently been shown to have RhoA regulatory functions...

Alternative Titles

Full title

Neuron-Specific Deletion of the Nf2 Tumor Suppressor Impairs Functional Nerve Regeneration

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1807560941

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1807560941

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0159718

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