Neuron-Specific Deletion of the Nf2 Tumor Suppressor Impairs Functional Nerve Regeneration
Neuron-Specific Deletion of the Nf2 Tumor Suppressor Impairs Functional Nerve Regeneration
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United States: Public Library of Science
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English
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United States: Public Library of Science
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In contrast to axons of the central nervous system (CNS), axons of the peripheral nervous system (PNS) show better, but still incomplete and often slow regeneration following injury. The tumor suppressor protein merlin, mutated in the hereditary tumor syndrome Neurofibromatosis type 2 (NF2), has recently been shown to have RhoA regulatory functions...
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Neuron-Specific Deletion of the Nf2 Tumor Suppressor Impairs Functional Nerve Regeneration
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TN_cdi_plos_journals_1807560941
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1807560941
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0159718