Mild Alkalization Acutely Triggers the Warburg Effect by Enhancing Hexokinase Activity via Voltage-D...
Mild Alkalization Acutely Triggers the Warburg Effect by Enhancing Hexokinase Activity via Voltage-Dependent Anion Channel Binding
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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To fully understand the glycolytic behavior of cancer cells, it is important to recognize how it is linked to pH dynamics. Here, we evaluated the acute effects of mild acidification and alkalization on cancer cell glucose uptake and glycolytic flux and investigated the role of hexokinase (HK). Cancer cells exposed to buffers with graded pH were mea...
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Mild Alkalization Acutely Triggers the Warburg Effect by Enhancing Hexokinase Activity via Voltage-Dependent Anion Channel Binding
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TN_cdi_plos_journals_1808041739
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1808041739
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0159529
